hemeonclinx Medical News about Human Colorectal Cancer Cells; Moscatilin

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Human Colorectal Cancer Cells; Moscatilin

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Moscatilin Induces Apoptosis in Human Colorectal Cancer Cells: A Crucial Role of c-Jun NH2-Terminal Protein Kinase Activation Caused by Tubulin Depolymerization and DNA Damage
Clinical Cancer Research, 07/07/08

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Free Abstract

Chen T-H et al. - These results suggest that moscatilin induces apoptosis of colorectal HCT-116 cells via tubulin depolymerization and DNA damage stress and that this leads to the activation of JNK and mitochondria-involved intrinsic apoptosis pathway.

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