hemeonclinx Medical News about autologous HSCT; high-dose melphalan; citrulline

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autologous HSCT; high-dose melphalan; citrulline

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Bacteraemia coincides with low citrulline concentrations after high-dose melphalan in autologous HSCT recipients
Bone Marrow Transplantation, 07/01/08

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Free Abstract

Herbers AHE et al. - Citrulline concentrations rapidly decline after Mel-200 reflecting intestinal mucosal barrier injury. Low citrulline, rather than the duration of neutropenia, is associated with bacteraemia indicating the importance of an intact mucosal barrier in neutropenic patients.

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