hemeonclinx Medical News about ovarian cancer cells; priming with EGFR inhibitors plus EGF

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ovarian cancer cells; priming with EGFR inhibitors plus EGF

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Priming with EGFR tyrosine kinase inhibitor and EGF sensitizes ovarian cancer cells to respond to chemotherapeutical drugs
Cancer Letters, 07/01/08

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Free Abstract

Cao C et al. - Taken together, the authors contend that priming with EGFR inhibitors plus EGF inhibits cell signaling pathways leading to cell proliferation and survival, while down-regulating EGFR. This priming approach sensitizes ovarian cancer cells and would ultimately result in better chemotherapeutical outcome.

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