Plichart M et al. - An additional evidence for a role of paternal smoking in central nervous system (CNS) tumors is provided; maternal coffee and tea consumption during pregnancy may also increase the risk. The study does not suggest an increased risk of CNS tumours related to alcohol consumption during pregnancy. Methods
The hypothesis that parental smoking, alcohol and caffeinated beverage consumption may play a role in the aetiology of childhood malignant CNS tumours was tested
Study included 209 incident cases of CNS tumours and 1681 population-based controls; age and sex matched
Data were collected through a standardized telephone interview of the biological mothers
Results
No association between maternal smoking during pregnancy and CNS tumours
Paternal smoking during the year before birth was associated with CNS tumours particularly astrocytomas
Maternal alcohol consumption during pregnancy was not associated with CNS tumours
Associations between ependymomas and the highest consumption of coffee and tea were observed
A strong association between CNS tumours and the highest maternal consumption of both coffee and tea during pregnancy was observed
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