Demirer AN et al. - When surgical resection is not possible, external beam radiotherapy (EBRT) may be used for palliative purpose to obtain local control for extensive disease as first-line therapy in follicular thyroid carcinoma. Methods
A case report of follicular thyroid carcinoma of a 52- yr-old woman with a 12-month history of progressively enlarging mass in the anterior chest wall
Results
Mass was fixed to the chest wall, measuring 12×10 cm in diameter
A lobulated soft-tissue mass (17×11×6 cm) destructing sternum and extending into the anterior mediastinum
No lung metastasis; invasion of tumor to the ascending aorta, superior vena cava, and right atrium could not be excluded
Multiple lymph nodes in the supraclavicular regions
46×37 mm nodule in the left lobe of thyroid glands with milimetric gross calcifications and cystic-necrotic areas
Hyperthyroidism was detected
Typical histology of follicular carcinoma
She was considered inoperable
Pt was treated with EBRT rather than radioiodine as first-line therapy
After a course of conventional radiation with 50 Gy in 25 fractions over 4 wks, tumor regressed remarkably in 6 mos
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