hemeonclinx Medical News about BCR-ABL-induced myeloproliferative disease; SKP2 expression

Click the title below to leave the MDLinx Network and go to the Journal's Website

Absence of SKP2 expression attenuates BCR-ABL-induced myeloproliferative disease
Blood, 06/25/08

Email This Article

Save in My Library

Free Abstract

These data identify SKP2 as a crucial mediator of BCR-ABL-induced leukemogenesis and provide the first in vivo evidence that SKP2 promotes oncogenesis. Hence stabilization of p27 by inhibiting its recognition by SCFSKP2 may be therapeutically useful.

--- BASIC SCIENCE/GENETICS TOP ARTICLES ---

Receive free subspecialty "5-minute updates" via email

Screening for prostate cancer: U.S. Preventive Services Task Force Recommendation Statement
Annals of Internal Medicine, 08/07/08

Ixabepilone: A new antimitotic for the treatment of metastatic breast cancer
Annals of Pharmacotherapy, 08/18/08

Body size and risk of luminal, HER2-overexpressing, and triple-negative breast cancer in postmenopausal women
Cancer Epidemiology, Biomarkers & Prevention, 08/21/08

...All of Basic Science/Genetics

Sponsor

--- MYELOPROLIFERATIVE DZ TOP ARTICLES ---

Receive free subspecialty "5-minute updates" via email

Quality-of-Life Assessment for Routine Oncology Clinical Practice
The Journal of Supportive Oncology, 06/16/08

Multiparameter flow cytometry remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation
Blood, 08/11/08

A multicenter, randomized clinical trial comparing zoledronic acid versus observation in patients with asymptomatic myeloma
Cancer, 08/07/08

...All of Myeloproliferative Dz