Hashii Y et al. – A novel treatment strategy is feasible for neuroblastoma pts at a high risk for relapse Methods
Study of novel treatment strategy: postponing primary surgery until after systemic chemotherapy, including high-dose chemotherapy (HDC) without interruption by local therapy
Treatment of 11 consecutive pediatric neuroblastoma pts
Administration of double-conditioning HDC: thiotepa and melphalan after induction chemotherapy
Radical surgery for local lesions; no irradiation to any lesions