hemeonclinx Medical News about Breast Cancer Cells; Stress Mediated Inhibition of Protein Synthesis

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Breast Cancer Cells; Stress Mediated Inhibition of Protein Synthesis

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Increased Susceptibility of Breast Cancer Cells to Stress Mediated Inhibition of Protein Synthesis
Cancer Research, 06/19/08

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Free Abstract

Pervin S et al. - These results suggest that NO-induced cytostasis in breast cancer cells was due to PKR activation and increased phosphorylation of eIF2-alpha, whereas the reduced susceptibility of normal mammary epithelial cells to NO could be due to the inaccessibility of PKR, which is bound to inhibitor p58.

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