hemeonclinx Medical News about human gliomas; M2 anti-inflammatory macrophage phenotype

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human gliomas; M2 anti-inflammatory macrophage phenotype

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Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas
The Journal of Pathology, 06/26/08

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Free Abstract

Komohara Y et al. - These results suggest that tumour-derived M-CSF induces a shift of microglia/macrophages towards the M2 phenotype, which influences tumour growth. Evaluation of the proportion of M2 microglia/macrophages and M-CSF expression in tumour tissue would be useful for assessment of microglia/macrophage proliferative activity and the prognosis of patients with gliomas.

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