Corn B et al. – Phosphorylated extracellular signal-regulated kinase (phospho-ERK) levels may serve as a prognostic marker in colorectal cancer based on findings in a pilot study Methods
Study of phospho-ERK staining level in pretreatment specimens and the effect of short-course radiation therapy (RT) on levels in colorectal cancer specimens from pts beginning RT before surgery
Results
Of 12 pts, 7 had positive stains for phospho-ERK before and/or after RT
Most phospho-ERK-positive pts before RT converted to ERK negativity after RT
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