Fujikawa A et al. - In a study to assess the use of a bi-annual CT screening for X-ray screening-negative subjects for 4 years, CT screening might have the potential to detect lung cancer with good prognostic factors not limited to early detection. Sufficiently long follow-up time would be required to evaluate the efficacy for decreasing lung cancer mortality with CT screening Methods
10 pts with lung cancer were detected among 22,720 person-year subjects through X-ray screening
Among the X-ray screening-negative subjects, 3305 subjects participated in a CT screening program resulting in detection of 15 pts with lung cancer
Results
All 15 cases detected by CT screening and 5 of the 10 cases detected by X-ray screening were at stage IA
In respect to gender, histological type and CT findings, pts detected by CT screening had a better prognostic profile than those detected by X-ray screening
Survival was significantly better in the former than the latter, both in its entirety comparison and in a comparison limited to pts who underwent surgery
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