Jansen CE et al. - Significant decreases in visuospatial skill and total cognitive scores were found following chemotherapy. In addition, a significant improvement was found in executive function. Of note, these changes remained significant even after controlling for anxiety, depression, fatigue, hemoglobin level, menopausal status, and perceived cognitive function. Data from this study supported the hypothesis that chemotherapy may have a negative impact on select domains of cognitive function.
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