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Ewing sarcoma Article Summary

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Ewing sarcoma of the rib-initial symptoms and clinical features: Tumor missed at the first visit in 21 of 26 patients
Acta Orthopaedica, 06/02/08
Print     Email This Article     Save in My Library   Free Abstract
Widhe B et al. - The most important clinical finding in Ewing sarcoma (EWS) of the rib was a palpable mass and pleural effusion. Both findings are rare in this age group and should be thoroughly investigated.

Methods
  • Study to examine the initial symptoms of EWS of the rib that could help to shorten the delay in diagnosis
  • Records of 26 consecutive pts were examined from the first visit for symptoms related to EWS of the rib
  • All pts were <30 yrs of age and had been diagnosed between 1981 and 2000
  • All pts had a minimum of 5 yrs of f/u

Results
  • A tumor was suspected at the first visit in only 5/26 pts; pleurisy was the most common misdiagnosis
  • 23 pts complained of pain, localized or pleuritic, and 11 had a palpable mass
  • 15/26 pts had chest radiographs taken at the first visit, but a tumor was suspected in only 4 cases
  • The most common radiographic finding was pleural effusion -- diagnosed in 10/15 pts
  • 23 pts were operated
  • In 6 pts no tumor was suspected before surgery
  • 12 pts died from the Ewing sarcoma
  • Median survival was 2.4 yrs
  • Doctor's delay was median 3.0 (0-10) mos, but it exceeded 7 mos in 4 pts
  • Patient's delay was 2.5 (0-10) mos

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