Yuvaraj S et al. – Tamoxifen (TAM) coadministered with coenzyme Q10, riboflavin and niacin (CoRN) has a positive effect on blood chemistry profiles in postmenopausal women with breast cancer Methods
Study of whether TAM coadministration with CoRN resolves in biochemical derangements induced by TAM alone in postmenopausal breast cancer pts
Vitamin supplementation with TAM for 90 days
Blood sampled at baseline and at days 45 and 90 during treatment
Blood chemistry profiles assessed in 78 untreated, sole TAM-treated, and combination-treated pts with 46 age- and sex-matched controls
Results
Treatment with combination TAM-CoRN showed a statistically significant improvement in blood chemistry parameters to near-normal levels