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Impact of preoperative antiandrogen medication Article Summary

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Impact of preoperative antiandrogen medication and nerve-sparing surgery on the outcome of radical prostatectomy
International Urology and Nephrology, 05/12/08
Print     Email This Article     Save in My Library   Free Abstract
Hodzic J et al. - Patients on antiandrogen medication, who had undergone nerve-sparing surgery have a higher quality of life (QoL).

Methods
  • Impact of antiandrogen medication on loss of blood and of nerve-sparing surgery on QoL was investigated
  • 401 men who underwent radical prostatectomy were asked about antiandrogenic medication prior to radical prostatectomy
  • Daily life activities, overall satisfaction, voiding ability, and sexual activities of pts were also noted
  • Consumption of erythrocyte concentrates and cryoprecipitated plasma was taken from the records

Results
  • During the 36 mo f/u, 72% pts replied
  • 23% of those who replied had received antiandrogen medication prior to radical prostatectomy
  • In 18% of the men, the nerve-sparing technique was used
  • In antiandrogen-medicated pts, an elevated consumption of erythrocyte concentrates and of cryoprecipitated plasma was observed
  • Pts who underwent the nerve-sparing technique reported better results in daily life activities, general health status, International Prostate Symptom Score (IPSS), and continence

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