Ficarra V et al. - In a study to review the most recent data on prognostic factors and describe the characteristics and prognostic accuracy of the most important prognostic systems available to predict the risk of recurrence, progression, and mortality in pts with renal cell carcinoma (RCC), it seems that the current prognostic systems can be improved through the inclusion of molecular and genetic variables Methods
The study was based on a non-systematic review of literature
Results
Clinical, anatomical, and histological factors are the most largely evaluated prognostic factors in RCC
Valuable prognostic accuracy has been shown for several laboratory parameters and a few genetical and molecular markers
A few integrating systems have been proposed and validated, integrating both clinical and pathological or only pathological variables