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Role of Genetic and Nongenetic Factors for Fluorouracil Treatment-Related Severe Toxicity
Journal of Clinical Oncology, 04/30/08
Print     Email This Article     Save in My Library   Free Abstract
Schwab M et al. - DPYD, TYMS, and MTHFR play a limited role for FU related toxicity but a pronounced DPYD gene/sex-interaction increases prediction rate for male patients. Toxicity risk assessment should include sex, mode of administration, and folinic acid as additional predictive factors.
 

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