Penel N et al. - After taking into account grade and metastasis at presentation, quality of surgery has prognostic value in the management of adult soft-tissue sarcomas. Methods
To assess prognostic factors and survival in the management of soft-tissue sarcomas, the experience of 45 recent successive cases was reviewed
Data were collected from a retrospective database and statistically analyzed
Rhabdomyosarcomas were excluded
Results
The mean age was 50.1 yrs; there were 24 men and 21 women
The main histological subtypes were undifferentiated sarcoma (14) and angiosarcoma (10); 46% of tumours were grade 3
The most frequent primary sites were neck muscles (33%) and scalp (24%)
At presentation, 20% of cases with lymph-node involvement and another 24% with distant metastasis were observed
The treatment was with curative intent in 73% cases
This entailed surgery, with adjuvant radiotherapy in 15 cases and adjuvant chemotherapy in 5 cases
The 5-yr OS was 52%
Poor prognostic factors were high grade, initial metastasis or lymph nodes, absence of surgery, and number of surgical procedures
Two factors were significant: grade and absence of surgery
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