Batista LI et al. - In a trial to assess the feasibility of coordinated prophylactic mastectomy (PM) and bilateral salpingo-oophorectomy (BSO) in hereditary breast-ovarian cancer syndrome, it was shown that coordinated PM and BSO is a feasible procedure with acceptable morbidity in selected high-risk pts that desire to undergo surgery at 1 operative setting Methods
High-risk women for breast and ovarian cancer who underwent coordinated PM and BSO were included
Clinical characteristics and surgical and oncologic outcomes were retrospectively reviewed
Results
12 pts underwent coordinated PM and BSO; 10 had history of previous breast cancer
Autologous breast reconstruction was performed in 10 pts
Mean age at surgery was 43; mean operating time was 9.3 hours with a mean postoperative hospitalization of 5.4 days
Postoperatively, 1 pt developed an abdominal wound dehiscence, another reoperation for flap congestion; 1 had umbilical superficial epidermolysis, and 1 developed aspiration pneumonia
At a mean follow-up of 84 months, 10 pts were cancer-free
Although no pts developed a new primary cancer, 2 developed a distant recurrence
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