hemeonclinx Medical News about Polymorphisms in the hMSH2 Gene

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Article Summary

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Polymorphisms in the hMSH2 Gene and the Risk of Primary Lung Cancer
Cancer Epidemiology, Biomarkers & Prevention, 04/14/06

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Free Abstract

Polymorphisms in the DNA repair genes may be associated with differences in the capacity to repair DNA damage, and so this can influence an individual's susceptibility to lung cancer. To test this hypothesis, we investigated the association of hMSH2 –118T>C, IVS1+9G>C, IVS10+12A>G, and IVS12–6T>C genotypes and their haplotypes with the risk of lung cancer in a Korean population

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