Molecular characterization of EGFR, PDGFRA and VEGFR-2 in cervical adenosquamous carcinoma Longatto-Filho A et al. - This is the most extensive analysis of EGFR, PDGFRA and VEGFR-2 in cervical adenosquamous carcinomas. Despite the absence of EGFR and PDGFRA activating mutations, the presence of overexpression of these three important therapeutic targets in a subset of cases may be important in predicting the sensitivity of adenosquamous carcinoma to specific anti-RTKs drugs. [more...]
