Analysis of the Ten-Eleven Translocation (TET)2 gene in familial myeloproliferative neoplasms Saint-Martin C et al. - Analysis of familial segregation confirmed that TET2 mutations were not inherited but somatically acquired. TET2 mutations were mainly observed (10/12) in patients with primary myelofibrosis (PMF) or patients with polycythemia vera (PV) or essential thrombocythemia (ET) who secondarily evolved towards myelofibrosis or acute myeloid leukemia. [more...]
