Involvement of the IGF system in fetal growth and childhood cancer: an overview of potential mechanisms Callan AC et al. - The review aims to draw together and summarize the literature linking the IGF system, rapidity of fetal growth, and risk of some specific childhood cancers; suggest explanations for some of the inconsistencies observed in previous studies of these associations; and propose an integrated framework for the putative involvement of the IGF system in the development of at least some childhood cancers. [more...]