Quantitative proteomics using formalin-fixed paraffin-embedded tissues of oral squamous cell carcinoma Negishi A et al. - The results suggest that epigenetic silencing of TGM3 plays certain roles in the process of oral carcinogenesis. The method for quantitative proteomic analysis of FFPE tissue described here offers new opportunities to identify disease-specific biomarkers and therapeutic targets using widely available archival samples with corresponding detailed pathological and clinical records. [more...]
