Epigenetic regulation of maspin expression in human ovarian carcinoma cells
Stephen L. Rose, et al. - Conclusions: These results suggest that changes in cytosine methylation and chromatin accessibility play an important role in maspin expression in human ovarian carcinoma. Deregulation of maspin expression in ovarian cancer is due to loss of epigenetic control as has been shown in other cancers. This observation provides further evidence of the strict epigenetic control of the maspin gene [more...]
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