Top prostate-specific antigen Articles in Oncology

Natural History of Persistently Elevated Prostate Specific Antigen After Radical Prostatectomy: Results From the SEARCH Database
The Journal of Urology, 10/16/2009

Moreira DM et al. – Prostate specific antigen persistence is associated with increased biochemical recurrence and overall mortality. In men with persistence the prostate specific antigen nadir is ... independent predictor of recurrence and mortality. Thus, prostate specific antigen persistence and nadir are important tools for early postoperative risk stratification. [more...]

Should Prostate Specific Antigen be Adjusted for Body Mass Index? Data From the Baltimore Longitudinal Study of Aging
The Journal of Urology, 11/12/2009

Loeb S et al. – Consistent with prior studies, we found an inverse relationship between obesity and serum prostate specific antigen. However, the magnitude of the difference ... small. Thus, adjusting prostate specific antigen for body mass index does not appear warranted. [more...]

Men Older Than 70 Years Have Higher Risk Prostate Cancer and Poorer Survival in the Early and Late Prostate Specific Antigen Eras
The Journal of Urology, 10/21/2009

Sun L et al. – Men older than 70 years had higher risk disease and poorer survival in the early and late prostate specific antigen eras. Pathological Gleason sums did not change between the 2 eras. Patient age was an important variable in prostate specific ... antigen screening, biopsy, treatment and prognosis. [more...]

Prostate specific antigen for early detection of prostate cancer: longitudinal study
British Medical Journal, 10/08/2009

Holmstrom B et al. – No single cut–off value for prostate specific antigen concentration attained likelihood ratios formally required for a screening test. Prostate specific antigen concentrations [more...]

Proton MRS detects metabolic changes in hormone sensitive and resistant human prostate cancer models CWR22 and CWR22r
Magnetic Resonance in Medicine, 10/09/2009

consistent with the observed immunohistochemistry changes, tumor growth inhibition for CWR22r, and a constant prostate specific antigen level versus increasing prostate specific antigen for control CWR22. Metabolic changes in total choline by proton MRSI can be used as an early biomarker of response [more...]

Evaluating the combined effect of comorbidity and prostate-specific antigen kinetics on the risk of death in men after prostate-specific antigen recurrence
Journal of Clinical Oncology, 11/02/2009

Wo JY et al. – Rapid PSA velocity at recurrence is significantly associated with an increased risk of ACM among patients with no or minimal [more...]

The effect of Gleason score on the predictive value of prostate-specific antigen doubling time
BJU International, 11/11/2009

Tollefson MK et al. – The PSA DT remains associated with outcome both before and after RP across increasing pathological Gleason scores, although the predictive ability of PSA DT is diminished in ... urology [more...]

Prostate-specific antigen screening of workers under the age of 40 in Japan
Cancer Epidemiology, 10/22/2009

Kawada T et al. – One–sixth of male workers attending the health check–up program were under 40 years of age. According to the criteria of the Japanese Urological Association, this examination program ... included younger subjects who were not candidates for PSA screening. [more...]

Analysis of T1c prostate cancers treated at very low prostate-specific antigen levels
International Braz J Urol, 11/06/2009

Stephenson AJ et al. – The pathologic features and outcome of patients treated at low PSA levels are favorable and similar for patients with PSA < or = 2.5 versus 2.6–4.0. However, > 50% of the former ... failed to identify a therapeutic benefit to the diagnosis of cancers below accepted PSA thresholds for biopsy. [more...]

Relationship Between Prostate-specific Antigen and Hematocrit: Does Hemodilution Lead to Lower PSA Concentrations in Men With a Higher Body Mass Index
Urology, 10/28/2009

Ohwaki K et al. – In healthy men with a BMI of 18.5–30 kg/m2, a lower hematocrit was significantly associated with a lower PSA ... lower PSA levels observed in men with a higher BMI, resulting in an inverse relationship between BMI and PSA. [more...]