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Pre-implantation Basiliximab Reduces Incidence of Early Acute Rejection in Pediatric Heart Transplantation
The Journal of Heart and Lung Transplantation, 12/04/09
Grundy N et al. – The results of this study confirm that basiliximab is effective at suppressing CD25 count whether given pre– or post–CPB. Basiliximab before transplantation appeared to reduce acute rejection, whereas post–CPB administration did not suggest similar effects. These findings require independent validation in randomized trials and further studies should seek to mechanistically delineate these observations.
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