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See Latest ArticlesTriptolide simultaneously induces reactive oxygen species, inhibits NF-kappaB activity and sensitizes 5-fluorouracil in colorectal cancer cell lines
Cancer Letters, 11/16/09
Xu B et al. – PG490 and 5–FU treatment induced activated caspase 3 and Bax expression and inhibited Bcl–2 expression. PG490 simultaneously induced generation of reactive oxygen species (ROS) and inhibited NF–kappaB transcriptional activity.
Today in Basic Science/Genetics...keeping you current
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Endocellular polyamine availability modulates epithelial-to-mesenchymal transition and unfolded protein response in MDCK cells
Laboratory Investigation, 03/19/10
Functional significance of the two ACOX1 isoforms and their crosstalks with PPAR[alpha] and RXR[alpha]
Laboratory Investigation, 03/19/10
Protein pathway biomarker analysis of human cancer reveals requirement for upfront cellular-enrichment processing
Laboratory Investigation, 03/19/10
Today in Colorectal Cancer/Polyps...keeping you current
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Health-related quality of life of colorectal cancer patients receiving oral UFT plus leucovorin compared with those with surgery alone
International Journal of Clinical Oncology, 03/19/10
Somatic mutations and losses of expression of microRNA regulation-related genes AGO2 and TNRC6A in gastric and colorectal cancers
The Journal of Pathology, 03/19/10
Thioredxin reductase inhibitor ethaselen increases the drug sensitivity of the colon cancer cell line LoVo towards cisplatin via regulation of G1 phase and reversal of G2/M phase arrest
Investigational New Drugs, 03/19/10
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