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Chang SM et al. – The CACS and SPECT findings are independent and complementary predictors of short– and long–term cardiac events. Despite a normal SPECT result, a severe CACS identifies subjects at high long–term cardiac risk. After a normal SPECT result, these findings support performing a CACS in patients who are at intermediate or high clinical risk for coronary artery disease to better define those who will have a high long–term risk for adverse cardiac events.

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