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Nitric oxide is not obligatory for radial artery flow-mediated dilation following release of 5 or 10 min distal occlusion
Heart And Circulatory Physiology, 11/04/09
Pyke KE et al. – RH following 10min of occlusion results in an enhanced stimulus and %FMD compared to 5min of occlusion. When the occlusion cuff is re–inflated 30s post release of a 10min occlusion it does not result in an enhanced %FMD compared to that which results from RH following 5min of occlusion. The lack of effect of L–NMMA on FMD suggests that NO may not be obligatory for radial artery FMD in response to either 5 or 10 min of occlusion in healthy volunteers.
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