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Identify drug-induced T wave morphology changes by a cell-to-electrocardiogram model and validation with clinical trial data
Journal of Electrocardiology, 11/03/09
Xue J et al. – The study provided preliminary results showing the usefulness of the cell–to–ECG model for studying relationship between multiple ion–channel factors with ECG morphology changes. The global and localized TDR generate very different T wave morphologies. The newly identified T wave morphology parameters are highly correlated with transmural dispersion and are heart rate independent.
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