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See Latest ArticlesConcurrent imaging of metabolic and electric signals in the heart
EurekAlert, 10/26/09
Cardiac rhythm disorders can result from disturbances in cardiac metabolism. These metabolic changes are tightly linked with specific cardiac electrophysiology abnormalities, such as depressed excitability, impaired intra– and extracellular conductivities, wave propagation block, and alteration of conduction velocity, action potential amplitude, and duration. The altered electrophysiology eventually can lead to arrhythmias, fibrillation, and cardiac death; therefore, understanding the spatiotemporal complexity of the relationship between metabolism and electrophysiology is the challenge in developing new approaches for treatment of cardiac diseases.
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