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See Latest ArticlesBeta-Adrenergic signaling accelerates and synchronizes cardiac ryanodine receptor response to a single L-type Ca2+ channel
Proceedings of the National Academy of Sciences of the United States of America, 10/21/09
Zhou P et al. – The results demonstrate unequivocally that RyR activation by a single LCC is accelerated and synchronized during beta–AR stimulation. This molecular mechanism of sympathetic regulation will permit more fundamental studies of altered beta–AR effects in cardiovascular diseases.
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