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See Latest ArticlesCardiovascular disease and intensive glucose control in type 2 diabetes mellitus: moving practice toward evidence-based strategies
Vascular Health and Risk Management, 10/21/09
Meier M et al. – VADT suggests that one possibility for the lack of observed effect of intensive therapy could be that the cardiovascular benefit is delayed. This contrasts strongly with the long–term postintervention outcomes of UKPDS, which show a persistent benefit of glycemic control during 10 years of post–trial follow–up (‘legacy effect’). Therefore, the best way to protect patients with T2DM against coronary and cerebrovascular disease is to target all cardiovascular risk factors as early as possible by an individualized approach.
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