Cardiology Medical News about Statin prophylaxis

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Statin prophylaxis and inflammatory mediators following cardiopulmonary bypass: a systematic review
Critical Care, 10/27/09

Morgan C et al. – Although the RCT evidence may suggest a reduction in post–CPB inflammation by statin therapy, the evidence is not definitive due to significant limitations. Several of the trials were not methodologically rigorous and statin intervention was highly variable in this small number of studies. This systematic review demonstrates that there is a significant gap that exists in the current literature in regards to the potential anti–inflammatory effect of statin therapy prior to CPB.

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