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See Latest ArticlesJAK/STAT Signaling Pathway Regulates Nox1 and Nox4-Based NADPH Oxidase in Human Aortic Smooth Muscle Cells
Arteriosclerosis, Thrombosis, and Vascular Biology, 10/22/09
Manea A et al. – JAK/STAT is a key regulator of Nox1 and Nox4 in human vascular SMCs. Inhibition of JAK/STAT pathway and the consequent Nox–dependent oxidative stress may be an efficient therapeutic strategy to reduce atherogenesis.
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