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See Latest ArticlesActivated complement is more extensively present in diseased aortic valves than naturally occurring complement inhibitors: a sign of ongoing inflammation
European Journal of Clinical Investigation, 10/16/09
Weeme MT et al. – The study indicates that anti–complement mediators (C1–inh and clusterin) are deposited in diseased aortic valves together with activated complement, indicating an existing counter response against complement locally in the valve. However, deposition of activated complement is significantly more widespread than that of its inhibitors, which could explain ongoing inflammation in those diseased aortic valves.
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