Cardiology

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Genetic screening of 104 patients with congenitally malformed hearts revealed a fresh mutation of GATA4 in those with atrial septal defects
Cardiology in the Young, 10/22/09

Hamanoue H et al. – The authors found only 1 novel mutation of GATA4 in those with atrial septal defecst. Analysis of the genetic background of the parents of the patient showed for the first time that a new mutation of GATA4 can cause sporadic atrial septal defects. They failed to discover any other mutations of either the GATA4 or NKX2–5 genes, supporting the marked genetic heterogeneity of human congenital cardiac defects.

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A selective endothelin-receptor antagonist to reduce blood pressure in patients with treatment-resistant hypertension: a randomised, double-blind, placebo-controlled trial
The Lancet, 10/27/09

Inflammatory mediators and premature coronary atherosclerosis in rheumatoid arthritis
Arthritis Care and Research , 11/03/09

Benefits and Difficulties in Measuring HDL Subfractions and Human Paraoxonase-1 Activity During Statin Treatment
Cardiovascular Drugs and Therapy, 11/03/09

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Oral Ibuprofen and Ductus Arteriosus Closure in Full-Term Neonates: A Prospective Case-Control Study
Pediatric Cardiology, 10/30/09

Adverse event rates in congenital cardiac catheterization- A multi-center experience
Catheterization and Cardiovascular Interventions, 11/06/09

Patent foramen ovale and cryptogenic stroke: a complex neuro–cardio–vascular problem
Expert Review of Cardiovascular Therapy , 11/12/09

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