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See Latest ArticlesAscorbic acid and tetrahydrobiopterin potentiate the EDHF phenomenon by generating hydrogen peroxide
Cardiovascular Research, 10/20/09
Garry A et al. – Pro–oxidant effects of AA and BH4 can enhance the EDHF phenomenon by generating H2O2, which has previously been shown to amplify electrotonic hyperpolarization–mediated relaxation by facilitating Ca2+ release from endothelial stores.
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Reduced expression of the sodium-calcium exchanger in adult cardiomyocytes via adenovirally delivered shrna results in resistance to simulated ischemic injury
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