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Effects of Adenosine and a Selective A2A Adenosine Receptor Agonist on Hemodynamic and Thallium-201 and Technetium-99m–SestaMIBI Biodistribution and Kinetics
JACC - Journal of the American College of Cardiology: Cardiovascular Imaging, 10/19/09
Mekkaoui C et al. – The bolus administration of regadenoson produced a hyperemic response comparable to a standard infusion of adenosine. The biodistribution and clearance of both 201Tl and 99mTc–sestaMIBI during regadenoson were similar to adenosine vasodilation. Ex vivo perfusion images under the most ideal conditions permitted detection of a critical stenosis, although 201Tl offered significant advantages over 99mTc–sestaMIBI for perfusion imaging during regadenoson vasodilator stress.
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