Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Pre-participation screening of young competitive athletes for prevention of sudden cardiac death 3. The Job Market for 2008-2009: Compensation 4. Renal Artery Stenosis 5. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease
Your Article Summary
See Latest ArticlesChronic doxorubicin cardiotoxicity is mediated by oxidative DNA damage-ATM-p53-apoptosis pathway and attenuated by pitavastatin through the inhibition of Rac1 activity
Journal of Molecular and Cellular Cardiology, 10/20/09
Yoshida M et al. – This data collectively suggest that doxorubicin–induced cardiotoxicity is mediated by oxidative DNA damage–ATM–p53–apoptosis pathway, and is attenuated by pitavastatin through its antioxidant effect involving Rac1 inhibition.
Related Articles
Dose-intensified epirubicin versus standard-dose epirubicin/cyclophosphamide followed by CMF in breast cancer patients with 10 or more positive lymph nodes: Results of a randomised trial (GABG-IV E-93) – The German Adjuvant Breast Cancer Group
European Journal of Cancer, 11/05/09
Relevance Score: 88%
Randomized phase III trial comparing docetaxel plus epirubicin versus docetaxel plus capecitabine as first-line treatment in women with advanced breast cancer
Annals of Oncology, 11/16/09
Relevance Score: 85%
Cyclophosphamide, epirubicin, and fluorouracil versus dose-dense epirubicin and cyclophosphamide followed by paclitaxel versus doxorubicin and cyclophosphamide followed by paclitaxel in node-positive or high-risk node-negative breast cancer
Journal of Clinical Oncology, 11/13/09
Relevance Score: 84%
A phase II trial of capecitabine and docetaxel followed by 5-fluorouracil/epirubicin/cyclophosphamide (FEC) as preoperative treatment in women with stage II/III breast cancer
Annals of Oncology, 10/26/09
Relevance Score: 84%
Sub-lethal doses of an anti-erbB2 antibody leads to death by apoptosis in cardiomyocytes sensitized by low pro-senescent doses of epirubicin: the protective role of dexrazoxane
Journal of Pharmacology and Experimental Therapeutics, 10/26/09
Relevance Score: 84%
Today in Physiology...keeping you current
Receive free subspecialty "5-minute updates" via email
Reduced expression of the sodium-calcium exchanger in adult cardiomyocytes via adenovirally delivered shrna results in resistance to simulated ischemic injury
Heart And Circulatory Physiology, 12/11/09
Progressive Muscle Metaboreflex Activation Gradually Decreases Spontaneous Heart Rate Baroreflex Sensitivity During Dynamic Exercise
Heart And Circulatory Physiology, 12/11/09
Over-expression of hepatocyte growth factor in smooth muscle cells regulates endothelial progenitor cells differentiation, migration and proliferation
International Journal of Cardiology, 12/10/09
Sponsor
Article Search
Sponsor
Sponsor