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Pleiotropic effects of neutrophils on myocyte apoptosis and left ventricular remodeling during early volume overload
Journal of Molecular and Cellular Cardiology, 10/19/09
Kolpakov MA et al. – The data support a functional role for neutrophils in MMP activation, ECM degradation, and myocyte apoptosis during eccentric cardiac hypertrophy and underscore the adverse effects of chronic anti–neutrophil therapy on cardiac remodeling induced by early volume overload.
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