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See Latest ArticlesNOS1AP Is a Genetic Modifier of the Long-QT Syndrome
Circulation, 10/16/09
Crotti L et al. – The findings indicate that NOS1AP, a gene first identified as affecting the QTc interval in a general population, also influences sudden death risk in subjects with LQTS. The association of NOS1AP genetic variants with risk for life–threatening arrhythmias suggests that this gene is a genetic modifier of LQTS, and this knowledge may be clinically useful for risk stratification for patients with this disease, after validation in other LQTS populations.
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