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Cooney MT et al. – This multivariable analysis, the largest of its kind to date, has confirmed the inverse, independent, strong and graded relationship between HDL–C and both CVD and CHD mortality. The authors have clarified previous suggestions that the relationship is stronger in women and that it applies in all age groups. This is the first prospective study to demonstrate the independent relationship specifically in healthy elderly women and to show that the relationship holds at all levels of total CVD risk.


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