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Coronary sinus concentrations of interleukin 6 and its soluble receptors are affected by reperfusion and may portend complications in patients with myocardial infarction
Atherosclerosis, 10/15/09
Kaminski KA et al. – Myocardial infarction increases concentration of IL–6 that is further elevated by reperfusion. A transcardiac gradient of sIL–6R during ischemia may indicate that large amounts of soluble IL–6 receptors are bound to the infarcted heart and thus affect signal transduction. IL–6 and initial sIL–6R gradient may portend complications in STEMI patients.
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