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Ciaccio EJ et al. – SDF appears less robust to additive interference, compared to the ODF and EA methods of estimating the activation rate at CFAE sites in this small group of patients. Use of optimized filter coefficients for DF measurement, or use of correlative methods such as EA, that reinforce the signal rather than filtering the noise, may improve calculation of activation rates.

Exclusive Author Commentary
Edward J. Ciaccio, 10/01/09

Ciaccio EJ et al. – the standard method of calculating dominant frequency (standard DF or SDF) in atrial fibrillation electrograms is tested against an optimized dominant frequency (ODF). The ODF method determines the filter parameters which maximize the power in the dominant frequency and its harmonics. We found that ODF is an improvement over SDF for determining the dominant frequency in the presence of additive noise and interference. As more interference is added, the DF estimation as calculated by SDF strays farther from the actual value obtained without additive interference, as compared to ODF. We also tested two autocorrelative techniques, ensemble average analysis (EA) and autocorrelation analysis (AC). It was found that EA is most robust to noise and interference as compared to the other methods (SDF, ODF, AC).

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