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Inhibition of 20-Hydroxyeicosatetraenoic Acid Synthesis Using Specific Plant Lignans. In Vitro and Human Studies
Hypertension, 09/30/09
Wu JHY et al. – This study demonstrates for the first time that sesame supplementation in humans reduces the plasma and urinary levels of 20–HETE, likely via inhibition of CYP4F2 by sesame lignans. These results suggest that sesame lignans could be used for the investigation of potential roles of 20–HETE in humans.
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