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Connective Tissue Growth Factor Promotes Fibrosis Downstream of TGFbeta and IL-6 in Chronic Cardiac Allograft Rejection
American Journal of Transplantation, 09/29/09
Booth AJ et al. – The findings indicate that CTGF functions as a downstream mediator of fibrosis in CR, and that CTGF neutralization may ameliorate fibrosis and hypertrophy associated with CR.
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