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Effects of 17-Hydroxyprogesterone on Tumor Necrosis Factor-alpha-Induced Hypertension During Pregnancy
American Journal of Hypertension, 09/30/09
Keiser SD et al. – Progesterone directly abolished TNF–alpha–stimulated ET–1 and attenuated TNF–alpha–induced hypertension, possibly via suppression of the renal ET–1 system. These data suggest that treatment with progesterone of hypertension associated with elevated cytokines during pregnancy may be worthy of further consideration.
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