Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Pre-participation screening of young competitive athletes for prevention of sudden cardiac death 3. The Job Market for 2008-2009: Compensation 4. Renal Artery Stenosis 5. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease
Your Article Summary
See Latest ArticlesGastrointestinal Bleeding in Patients With Acute Coronary Syndromes: Incidence, Predictors, and Clinical Implications
JACC - Journal of the American College of Cardiology, 09/23/09
Nikolsky E et al. – GIB is a serious condition in the scenario of ACS and is independently associated with mortality and ischemic complications.
Dr. Eugenia Nikolsky, 09/23/09
| Gastorintestinal bleeding is a rare but very serious condition in the setting of acute coronary syndromes, and is aasociated with high rates of mortality, myocardial infarction and stent thrombosis. Incidence of GIB is increased in elderly, smokers and patients with baseline anemia. Future trials should be directed at assessing measures to prevent GIB in vulnerable populations. According to the randomized FAMOUS trial recently published in the Lancet journal, H2-receptor inhibitor famotidine significantly reduces rates of gastric and duodenal ulcers, and erosive oesophagitis in patients taking low-dose aspirin. This drug therefore may be considered for primary prevention of GIB in patients at risk treated with antiplatelet therapy. Results of randomized COGENT trial will be announced at TCT 2009 this week to show whether combination of clopidogrel plus omeprazole compared to clopidogrel alone is safe and effective in reducing incidence of GIB, in patients treated with aspirin. |
Related Articles
Acute Coronary Syndromes: Diagnosis and Management, Part II
Mayo Clinic Proceedings, 11/03/09
Relevance Score: 97%
Management of acute coronary syndrome in a case of Behcets disease
Blood Coagulation & Fibrinolysis, 11/03/09
Relevance Score: 97%
Predictive Values of Post-Treatment Adenosine Diphosphate–Induced Aggregation and Vasodilator-Stimulated Phosphoprotein Index for Stent Thrombosis After Acute Coronary Syndrome in Clopidogrel-Treated Patients
The American Journal of Cardiology, 10/15/09
Relevance Score: 97%
Management of Spontaneous Coronary Artery Dissection: Review of the Literature and Discussion Based on a Series of 12 Young Women with Acute Coronary Syndrome
Cardiology, 10/12/09
Relevance Score: 97%
Spontaneous coronary artery dissection: a report of two atypical cases
Heart and Vessels, 10/06/09
Relevance Score: 96%
Today in Coronary Artery Disease...keeping you current
Receive free subspecialty "5-minute updates" via email
Associations of genetic polymorphisms of arachidonate 5-lipoxygenase-activating protein with risk of coronary artery disease in a European–American population
Atherosclerosis, 12/07/09
Qualitative assessment of previous evidence and an updated meta-analysis confirms lack of association between the ESR1 rs2234693 (PvuII) variant and coronary heart disease in men and women
Atherosclerosis, 12/07/09
Prospective, randomized, single-blind comparison of effects of 6 months of treatment with telmisartan versus enalapril on high-molecular-weight adiponectin concentrations in patients with coronary artery disease
Clinical Therapeutics, 12/07/09
Today in Interventional...keeping you current
Receive free subspecialty "5-minute updates" via email
Percutaneous coronary intervention following thrombolysis: For whom and when
Acute Cardiac Care, 12/07/09
A Novel 3-D Reconstruction System for the Assessment of Bifurcation Lesions Treated by the Mini-Crush Technique
Journal of Interventional Cardiology, 12/07/09
Prehospital 12-Lead ECG to Triage ST-Elevation Myocardial Infarction and Emergency Department Activation of the Infarct Team Significantly Improves Door-to-Balloon Times
Circulation: Cardiovascular Interventions, 12/03/09
Sponsor
Article Search
Sponsor
Sponsor